Mouse Ext2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ext2
Locus ID	14043
Kit Components	GA201324G1, Ext2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201324G2, Ext2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201324G3, Ext2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010163, NM_001355075, NM_001355076
Synonyms	AI893565
Summary	Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan.[UniProtKB/Swiss-Prot Function]

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