Mouse Eomes activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eomes
Locus ID	13813
Kit Components	GA201248G1, Eomes gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201248G2, Eomes gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201248G3, Eomes gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164789, NM_010136
Synonyms	C77258; TBR-2; Tbr2
Summary	Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.[UniProtKB/Swiss-Prot Function]

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