Mouse Eef2k activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eef2k
Locus ID	13631
Kit Components	GA201188G1, Eef2k gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201188G2, Eef2k gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201188G3, Eef2k gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001251826, NM_001267710, NM_001267711, NM_007908
Synonyms	C86191; eEF-2K
Summary	Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.[UniProtKB/Swiss-Prot Function]

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