Mouse Eda activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eda
Locus ID	13607
Kit Components	GA201172G1, Eda gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201172G2, Eda gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201172G3, Eda gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001177937, NM_001177938, NM_001177939, NM_001177940, NM_001177941, NM_001177942, NM_001177943, NM_001177944, NM_010099
Synonyms	Ed1; Eda-A1; Eda-A2; EDA1; HED; Ta; tabby; Tnlg7c; XLHED
Summary	Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. Isoform TAA binds only to the receptor EDAR, while isoform TA-A2 binds exclusively to the receptor EDA2R (By similarity). May also play a role in cell adhesion (PubMed:10534613).[UniProtKB/Swiss-Prot Function]

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