Mouse Ebf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ebf2
Locus ID	13592
Kit Components	GA201164G1, Ebf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201164G2, Ebf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201164G3, Ebf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001276387, NM_010095, NM_001360202
Synonyms	D14Ggc1e; EBF-2; Mmot1; O/E-3; OE-3
Summary	Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.[UniProtKB/Swiss-Prot Function]

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