Mouse Arid3a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arid3a
Locus ID	13496
Kit Components	GA201131G1, Arid3a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201131G2, Arid3a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201131G3, Arid3a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001288625, NM_001288626, NM_007880
Synonyms	Bright; Dri1; Dril1
Summary	Transcription factor involved in B-cell differentiation. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. May be involved in the control of cell cycle progression by the RB1/E2F1 pathway.[UniProtKB/Swiss-Prot Function]

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