Mouse Dhfr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dhfr
Locus ID	13361
Kit Components	GA201069G1, Dhfr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201069G2, Dhfr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201069G3, Dhfr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010049
Synonyms	8430436I03Rik; AA607882; AI662710; AW555094
Summary	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (PubMed:25980602). Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (PubMed:25980602). Binds its own mRNA.[UniProtKB/Swiss-Prot Function]

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