Mouse Dao activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dao
Locus ID	13142
Kit Components	GA201014G1, Dao gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201014G2, Dao gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201014G3, Dao gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286396, NM_001286397, NM_010018
Synonyms	AI987963; DAAO; DAMOX; Dao-1; Dao1
Summary	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.[UniProtKB/Swiss-Prot Function]

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