Mouse Cit activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cit
Locus ID	12704
Kit Components	GA200737G1, Cit gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200737G2, Cit gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200737G3, Cit gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007708
Synonyms	C030025P15Rik; Cit-k; CRIK; CRIK-SK
Summary	Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Probable RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.[UniProtKB/Swiss-Prot Function]

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