Mouse Cckar activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cckar
Locus ID	12425
Kit Components	GA200575G1, Cckar gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200575G2, Cckar gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200575G3, Cckar gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347354, NM_009827
Synonyms	AW106902
Summary	Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).[UniProtKB/Swiss-Prot Function]

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