Mouse Cbs activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cbs
Locus ID	12411
Kit Components	GA200567G1, Cbs gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200567G2, Cbs gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200567G3, Cbs gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271353, NM_144855, NM_178224
Synonyms	AI047524; AI303044; HIP4
Summary	Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).[UniProtKB/Swiss-Prot Function]

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