Mouse Cast activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cast
Locus ID	12380
Kit Components	GA200546G1, Cast gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200546G2, Cast gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200546G3, Cast gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001301153, NM_001301155, NM_001301156, NM_001301157, NM_001301158, NM_001301160, NM_001301181, NM_009817
Summary	This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each other. Some isoforms may be tissue-specific. Two different pseudogenes of this gene are found on chromosome 19. [provided by RefSeq, Jul 2014]

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