Mouse Casp9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Casp9
Locus ID	12371
Kit Components	GA200542G1, Casp9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200542G2, Casp9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200542G3, Casp9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001277932, NM_015733
Synonyms	AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
Summary	This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]

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