Mouse Canx activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Canx
Locus ID	12330
Kit Components	GA200509G1, Canx gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200509G2, Canx gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200509G3, Canx gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110499, NM_001110500, NM_007597
Synonyms	1110069N15Rik; AI988026; Cnx; D11Ertd153e
Summary	Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.[UniProtKB/Swiss-Prot Function]

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