Mouse Calca activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Calca
Locus ID	12310
Kit Components	GA200495G1, Calca gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200495G2, Calca gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200495G3, Calca gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033954, NM_001289444, NM_007587
Synonyms	CA; Calc; Calc1; Cgrp; CGRP-1; CGRP1; Ct; Ctn
Summary	This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]

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