Mouse Cacna1e activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cacna1e
Locus ID	12290
Kit Components	GA200479G1, Cacna1e gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200479G2, Cacna1e gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200479G3, Cacna1e gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009782
Synonyms	A430040I15; alpha1E; BII; Cach6; Cacnl1a6; Cav2.3; Cchra1
Summary	This gene encodes an integral membrane protein that belongs to the calcium channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing. [provided by RefSeq, Jul 2008]

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