Mouse Serping1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Serping1
Locus ID	12258
Kit Components	GA200458G1, Serping1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200458G2, Serping1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200458G3, Serping1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009776
Synonyms	C1INH; C1nh
Summary	Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. May inhibit chymotrypsin and kallikrein.[UniProtKB/Swiss-Prot Function]

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