Mouse Bcl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bcl3
Locus ID	12051
Kit Components	GA200388G1, Bcl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200388G2, Bcl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200388G3, Bcl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_033601
Synonyms	AI528691; Bcl-3
Summary	Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity). In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation.[UniProtKB/Swiss-Prot Function]

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