Mouse Apoa2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apoa2
Locus ID	11807
Kit Components	GA200237G1, Apoa2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200237G2, Apoa2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200237G3, Apoa2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013474, NR_131173
Synonyms	Alp-2; Apo-AII; Apoa-2; ApoA-II; ApoAII; Hdl-1
Summary	This gene encodes a component of high density lipoproteins (HDL). Mice lacking the encoded protein have low HDL-cholesterol levels, smaller HDL particles, increased clearance of triglyceride-rich lipoproteins and insulin hypersensitivity. Transgenic mice overexpressing the encoded protein have elevated levels of HDL-cholesterol and show increased susceptibility to atherosclerosis. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]

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