Mouse Aplp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aplp2
Locus ID	11804
Kit Components	GA200235G1, Aplp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200235G2, Aplp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200235G3, Aplp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001102455, NM_001102456, NM_009691, NM_001357698
Synonyms	AI790698; APLP-2
Summary	May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein (By similarity). Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.[UniProtKB/Swiss-Prot Function]

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