Mouse Api5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Api5
Locus ID	11800
Kit Components	GA200232G1, Api5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200232G2, Api5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200232G3, Api5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001305258, NM_007466, NM_001349003
Synonyms	AAC-11; AI196452; API-5
Summary	Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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