Mouse Alox5ap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alox5ap
Locus ID	11690
Kit Components	GA200171G1, Alox5ap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200171G2, Alox5ap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200171G3, Alox5ap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308462, NM_009663
Synonyms	Flap
Summary	Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).[UniProtKB/Swiss-Prot Function]

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