Mouse Aicda activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aicda
Locus ID	11628
Kit Components	GA200136G1, Aicda gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200136G2, Aicda gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200136G3, Aicda gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009645
Synonyms	Aid; Arp2
Summary	Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.[UniProtKB/Swiss-Prot Function]

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