Mouse Adam8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adam8
Locus ID	11501
Kit Components	GA200071G1, Adam8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200071G2, Adam8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200071G3, Adam8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291066, NM_007403
Synonyms	ADAM 8; CD156; CD156a; E430039A18Rik; MS2
Summary	This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]

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