Mouse Adam5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adam5
Locus ID	11499
Kit Components	GA200069G1, Adam5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200069G2, Adam5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200069G3, Adam5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001272057, NM_001272058, NM_001272059, NM_007401
Synonyms	tMDC II; tMDCII
Summary	This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. This gene is located in a cluster of related ADAM genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]

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