Human Occludin (OCLN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OCLN
Locus ID	100506658
Kit Components	GA119306G1, Occludin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA119306G2, Occludin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA119306G3, Occludin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205254, NM_001205255, NM_002538
Synonyms	BLCPMG; PPP1R115
Summary	This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

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