Human CDK11A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDK11A
Locus ID	728642
Kit Components	GA118961G1, CDK11A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118961G2, CDK11A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118961G3, CDK11A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001313896, NM_001313982, NM_024011, NM_033529, NR_132739, NR_132740
Synonyms	CDC2L2; CDC2L3; CDK11-p46; CDK11-p58; CDK11-p110; p58GTA; PITSLRE
Summary	This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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