Human INS-IGF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	INS-IGF2
Locus ID	723961
Kit Components	GA118882G1, INS-IGF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118882G2, INS-IGF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118882G3, INS-IGF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042376, NM_001042377, NR_003512
Synonyms	INSIGF
Summary	This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]

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