Human XAGE1 (XAGE1E) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XAGE1B
Locus ID	653067
Kit Components	GA118818G1, XAGE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118818G2, XAGE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118818G3, XAGE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001097603, NM_001097604, NM_001097605, NR_033257
Synonyms	xage-1 p16; X antigen family, member 1E; X antigen family member 1E
Summary	This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]

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