Human LYPD8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LYPD8
Locus ID	646627
Kit Components	GA118782G1, LYPD8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118782G2, LYPD8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118782G3, LYPD8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001085474, NM_001291283
Summary	Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis.[UniProtKB/Swiss-Prot Function]

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