Human PIRT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIRT
Locus ID	644139
Kit Components	GA118726G1, PIRT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118726G2, PIRT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118726G3, PIRT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001101387
Summary	Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity).[UniProtKB/Swiss-Prot Function]

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