Human MAP1LC3B2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP1LC3B2
Locus ID	643246
Kit Components	GA118686G1, MAP1LC3B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118686G2, MAP1LC3B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118686G3, MAP1LC3B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001085481
Synonyms	ATG8G
Summary	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).[UniProtKB/Swiss-Prot Function]

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