Human ECSCR activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ECSCR
Locus ID	641700
Kit Components	GA118659G1, ECSCR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118659G2, ECSCR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118659G3, ECSCR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077693, NM_001293739, NR_121659
Synonyms	ARIA; ECSM2
Summary	The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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