Human CHAC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHAC2
Locus ID	494143
Kit Components	GA118587G1, CHAC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118587G2, CHAC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118587G3, CHAC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001008708, NM_001346127
Synonyms	ChaC, cation transport regulator-like 2; ChaC, cation transport regulator homolog 2 (E. coli)
Summary	The protein encoded by this gene is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. It is thought that this gene is upregulated in response to endoplasmic reticulum stress and that the glutathione depletion enhances apoptosis. [provided by RefSeq, Sep 2016]

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