Human ASTL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ASTL
Locus ID	431705
Kit Components	GA118421G1, ASTL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118421G2, ASTL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118421G3, ASTL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002036
Synonyms	SAS1B
Summary	Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).[UniProtKB/Swiss-Prot Function]

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