Human Folate Receptor 4 (IZUMO1R) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IZUMO1R
Locus ID	390243
Kit Components	GA118139G1, Folate Receptor 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118139G2, Folate Receptor 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118139G3, Folate Receptor 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080486, NM_001199206
Synonyms	folate receptor 4 (delta) homolog; folate receptor 4 (delta) homolog (mouse); Folbp3
Summary	Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB/Swiss-Prot Function]

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