Human BLOC1S3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BLOC1S3
Locus ID	388552
Kit Components	GA117965G1, BLOC1S3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117965G2, BLOC1S3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117965G3, BLOC1S3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_212550
Synonyms	BLOS3; HPS8; RP
Summary	This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism. [provided by RefSeq, Jul 2008]

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