Human NSUN4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NSUN4
Locus ID	387338
Kit Components	GA117885G1, NSUN4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117885G2, NSUN4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117885G3, NSUN4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256127, NM_001256128, NM_199044, NR_045789, NR_045790, NR_045791
Synonyms	SHTAP
Summary	Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.[UniProtKB/Swiss-Prot Function]

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