Human AMIGO2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AMIGO2
Locus ID	347902
Kit Components	GA117669G1, AMIGO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117669G2, AMIGO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117669G3, AMIGO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143668, NM_181847, NM_001370299
Synonyms	ALI1; AMIGO-2; DEGA
Summary	Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.[UniProtKB/Swiss-Prot Function]

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