Human SLC35B2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC35B2
Locus ID	347734
Kit Components	GA117662G1, SLC35B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117662G2, SLC35B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117662G3, SLC35B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286509, NM_001286510, NM_001286511, NM_001286512, NM_001286513, NM_001286517, NM_001286519, NM_001286520, NM_178148
Synonyms	PAPST1; SLL; UGTrel4
Summary	Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 [PubMed 12716889]).[supplied by OMIM, Mar 2008]

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