Human LEUTX activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LEUTX
Locus ID	342900
Kit Components	GA117548G1, LEUTX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117548G2, LEUTX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117548G3, LEUTX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143832, NR_003931
Summary	Paired-like homeobox transcription factor involved in embryogenesis (PubMed:27578796, PubMed:30479355). May act as a regulator of embryo genome activation (PubMed:27578796). Binds to a 36 bp DNA elements containing a 5'-TAATCC-3' sequence motif, referred to as EEA motif (EGA-enriched Alu-motif), present in the promoters of target genes activated in early embryos (PubMed:27578796, PubMed:30479355).[UniProtKB/Swiss-Prot Function]

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