Human NACA2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NACA2
Locus ID	342538
Kit Components	GA117539G1, NACA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117539G2, NACA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117539G3, NACA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_199290
Synonyms	ANAC; NACAL
Summary	Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).[UniProtKB/Swiss-Prot Function]

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