Human FREM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FREM2
Locus ID	341640
Kit Components	GA117522G1, FREM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117522G2, FREM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117522G3, FREM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_207361
Synonyms	DKFZp686J0811; DKFZp781I048; KIAA1074
Summary	This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]

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