Human RSPO2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RSPO2
Locus ID	340419
Kit Components	GA117479G1, RSPO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117479G2, RSPO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117479G3, RSPO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282863, NM_001317942, NM_178565
Synonyms	CRISTIN2
Summary	This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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