Human Tetraspanin 33 (TSPAN33) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSPAN33
Locus ID	340348
Kit Components	GA117472G1, Tetraspanin 33 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117472G2, Tetraspanin 33 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117472G3, Tetraspanin 33 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178562
Synonyms	PEN; PEN.; TSPAN-33
Summary	Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).[UniProtKB/Swiss-Prot Function]

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