Human FAM5C (BRINP3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BRINP3
Locus ID	339479
Kit Components	GA117428G1, FAM5C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117428G2, FAM5C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117428G3, FAM5C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317188, NM_199051
Synonyms	DBCCR1L; DBCCR1L1; FAM5C
Summary	This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

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