Human ARL16 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARL16
Locus ID	339231
Kit Components	GA117410G1, ARL16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117410G2, ARL16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117410G3, ARL16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040025, NM_001329608, NM_001329609, NR_138058, NR_138059, NR_138060
Synonyms	ADP-ribosylation factor-like 16
Summary	The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). This protein has been shown to have an inhibitory role in the cellular antiviral response. This gene product interacts with the C-terminal domain of the DEXD/H-box helicase 58 (DDX58) gene product. This interaction was found to suppress the association between the DDX58 gene product and RNA, thereby negatively regulating the activity of the DDX58 gene product. [provided by RefSeq, Jul 2016]

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