Human NLRP14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NLRP14
Locus ID	338323
Kit Components	GA117364G1, NLRP14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117364G2, NLRP14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117364G3, NLRP14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_176822
Synonyms	CLR11.2; GC-LRR; NALP14; NOD5; PAN8
Summary	The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

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