Human DPH3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DPH3
Locus ID	285381
Kit Components	GA117220G1, DPH3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117220G2, DPH3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117220G3, DPH3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001047434, NM_206831
Synonyms	DELGIP; DELGIP1; DESR1; DPH3A; KTI11; ZCSL2
Summary	This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]

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