Human SUMF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SUMF1
Locus ID	285362
Kit Components	GA117217G1, SUMF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117217G2, SUMF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117217G3, SUMF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164674, NM_001164675, NM_182760
Synonyms	AAPA3037; FGE; UNQ3037
Summary	This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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